Journal: Veterinary Sciences
Article Title: Development of an Indirect ELISA Based on a Recombinant Chimeric Protein for the Detection of Antibodies against Bovine Babesiosis
doi: 10.3390/vetsci5010013
Figure Lengend Snippet: ROC analysis for the rMABbo-iELISA . ( A ) Interactive dot plot of the frequency distribution based on 300 known negative sera from tick-free regions of Argentina and 75 known positive sera from experimentally B. bovis infected bovines with the attenuated R1A strain. The horizontal line shows the cutoff value of ≥35%, providing a sensitivity of 95.9% and a specificity of 94.3% ( B ). Sensitivity and 100—Specificity values are plotted on the y -axis and x -axis, respectively. Red thick line indicates the fitted ROC curve and thin blue lines indicate the 95% confidence interval of the fitted ROC curve.
Article Snippet: The cutoff point for rMABbo-iELISA was established with the ROC curve (95% confidence interval) using MedCalc Statistical Software version 15.4 (MedCalc Software bvba, Ostend, Belgium; https://www.medcalc.org ; 2015).
Techniques: Infection